How Does T-scan Imaging of the Breast Work?
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The T-scan imaging system is similar in
size and appearance to an ultrasound system. There is a small
cart-mounted unit with a monitor and keyboard. The patient holds a metallic
wand that is similar in size and appearance to a "joy-stick" on many computer
games. One to two and a half volts (1.0V to 2.5V) of compatible alternating (AC)
electrical current are generated by the system and conducted through the body from the
wand held by the patient. When the scanning probe is placed against the skin of the breast
the electrical circuit is completed. Gel is used as an agent to improve conductivity
between the skin of the breast and the scanning probe (similar to ultrasound). A minuscule
amount of electric current is used, approximately the same amount produced by a small
penlight battery. The procedure creates no discomfort, and in most patients, no
sensation.
The scanning probe is moved over the
breast and its many sensors measures the current signal at the skin level. The computer
then reconstructs this information and shows images immediately on the monitor. The
scanning probe uses 256 sensors in high-resolution mode and 64 sensors in
normal-resolution mode. Images of the electrical impedance
profile of the breast are produced in real-time and are displayed as a 256-level gray
scale map of capacitance and conductivity properties of the breast. The image is recorded
into 9 sectors on a 3 x 3-sector matrix electrical impedance map of the breast. Targeted
electrical impedance views may be recorded using the anatomic screen.
Impedance objects are
defined as spots or regions that are brighter (or occasionally darker) than their
surrounding sector image. The only white object that should occur in T-scan examination of
a normal breast is the nipple. Skin marks such as moles, insect bites, or recent biopsy
locations can also show as bright spots and must be annotated by the operator so they are
not confused with cancerous abnormalities. Under normal conditions, the nipple image
should be the same size and symmetrical for both breasts.

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| This figure shows how the scanning
probe is held against the breast and measures the low level current that is conducted
through the breast tissue in the region of interest. Normal tissue has a high impedance
(low conductivity), malignant (cancerous) tissue has a lower impedance (higher
conductivity). The measured signals are then digitally processed by the system's computer
and displayed immediately as an image on the monitor. Image courtesy of Siemens Medical Solutions, www.medical.siemens.com |
Cancer cells have lower
electrical impedance than healthy cells. When the T-scan signal is displayed on the
computer screen, possible tumors show up as bright white spots. Cytological (cellular) and
histological (tissue) changes in cancerous tissue, including changes in cellular water and
electrolyte content and cell membrane properties, cause a significant change in tissue
electrical impedance (20-40 times lower than normal tissue), enabling cancerous and
pre-cancerous lesions to be visualized.
Updated: January 27, 2000
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